Panacetein

1.You will be given an unknown sample. Weigh it and use all of it.

2.For "Separation of Aspirin" on the middle of page 32, we will be using 5% sodium bicarbonate solution (NaHCO3), instead of 1M sodium hydroxide. Sodium hydroxide sometimes reacts with the ester group of aspirin.

3.For "Isolation of the Unknown Component" on the bottom of page 32, we will do the following:

a.Weigh your clean and dry 100 mL round-bottomed flask.

b.Transfer your dichloromethane layer form the separation of Aspirin to the round-bottomed flask.

c.Put a label on your cork ring with your name on it.

d.Take your round-bottomed flask and the cork ring to the rotary evaporators in the back of the room, and have your dichloromethane removed. If the rotary evaporators are in use, leave them there.

e.When your dichloromethane has been removed, reweigh the flask to determine the mass of the unknown.

4.After you have isolated the unknown in step 3 above, scrape it out into a 125 mL Erlenmeyer flask. Any remaining unknown can be removed from the flask by rinsing the flask with a few mL of boiling water.

5.Be sure to allow your aspirin and unknown to dry thoroughly before you weigh them and determine their melting point ranges.

Lab Report Format for Separating the Components of "Panacetin" (2) and Recrystallization and Melting Point Measurement: Identifying the Components of "Panacetin" (3).

1. Title Page

a.A descriptive title with between 15-25 words.

b.Dates the experiment was performed.

c.Course and section numbers.

d.Your name

e.Tape your TLC plate to the bottom of the page. Clearly label each column of spots on the page so I know what it is.

2. Body of the report (start a new page)

a.Panacetin sample number.

b.Weight of initial panacetin sample.

c.Weight of sucrose collected.

d.Weight of aspirin collected.

e.Melting